863312-38-3Relevant academic research and scientific papers
Total synthesis of the Strychnos alkaloid (+)-minfiensine: Tandem enantioselective intramolecular Heck-iminium ion cyclization
Dounay, Amy B.,Humphreys, Philip G.,Overman, Larry E.,Wrobleski, Aaron D.
, p. 5368 - 5377 (2008/12/22)
A 1,2,3,4-tetrahydro-9a,4a-(iminoethano)-9H-carbazole (4) is a central structural feature of the Strychnos alkaloid minfiensine (1) and akuammiline alkaloids such as vincorine (5) and echitamine (6). A cascade catalytic asymmetric Heck-iminium cyclization
Sequential catalytic asymmetric Heck-iminium ion cyclization: Enantioselective total synthesis of the Strychnos alkaloid minfiensine
Dounay, Amy B.,Overman, Larry E.,Wrobleski, Aaron D.
, p. 10186 - 10187 (2007/10/03)
A catalytic asymmetric method for the chemical synthesis of alkaloids containing the 1,2,3,4-tetrahydro-9a,4a-(iminoethano)-9H-carbazole (1) moiety is reported and verified by the enantioselective total synthesis of (+)-minfiensine (4). The central step i
