863400-99-1Relevant academic research and scientific papers
Efficient synthesis of functionalized oligodeoxyribonucleotides with base-labile groups using a new silyl linker
Ohkubo, Akihiro,Kasuya, Rintaro,Aoki, Katsufumi,Kobori, Akio,Taguchi, Haruhiko,Seio, Kohji,Sekine, Mitsuo
, p. 5345 - 5351 (2008/12/21)
In this study, we developed new 3′-terminal deoxyribonucleoside-loading reagents 1 with a new silyl-type linker. These reagents could increase the efficiency of introduction of 3′-terminal deoxyribonucleoside components into polymer supports to a level of
SILYL LINKER FOR SOLID-PHASE SYNTHESIS OF NUCLEIC ACID
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Page/Page column 3; 4, (2010/11/24)
The purpose of the invention is to develop a silyl linker that can be efficiently introduced on a solid-phase support used for the synthesis of nucleic acid oligomers such as DNA. The present invention relates to a silyl linker for use in the solid-phase
