863409-93-2Relevant academic research and scientific papers
Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design
Cook, Brian N.,Bentzien, J?rg,White, Andre,Nemoto, Peter A.,Wang, Ji,Man, Chuk C.,Soleymanzadeh, Fariba,Khine, Hnin Hnin,Kashem, Mohammed A.,Kugler Jr., Stanley Z.,Wolak, John P.,Roth, Gregory P.,De Lombaert, Stéphane,Pullen, Steven S.,Takahashi, Hidenori
scheme or table, p. 773 - 777 (2009/08/15)
Interleukin-2 inducible T-cell kinase (ITK) is a member of the Tec kinase family and is involved with T-cell activation and proliferation. Due to its critical role in acting as a modulator of T-cells, ITK inhibitors could provide a novel route to anti-inf
