863479-37-2

Upstream product

• 53560-33-1 3,4,5-trimethoxyphenylacetylene 
• 7732-18-5 water 
• 274-07-7 benzo[1,3,2]dioxaborole 

Downstream Products

• 1334163-01-7 (E)-3((E)-4-(3,4,5-trimethoxyphenyl)but-3-en-2-ylidene)benzofuran-2-one 

Relevant academic research and scientific papers

N-B dative bond-induced [3.3.0] bicyclic boronate-tethered exo-selective intramolecular Diels-Alder reaction

We report herein a highly exo-selective intramolecular Diels-Alder reaction of alkenyl boronates which employs an N-B dative bond-involved bicyclic rigid tether. Complex C(sp3)-rich polycyclic molecules containing up to 8 stereocenters can be readily formed via an operationally simple two-step procedure.

Synthesis and biological evaluation of vinylogous combretastatin A-4 derivatives

Stereospecific syntheses of the Z-E and E-Z vinylogues of combretastatin A-4, and two B-ring related analogues, were achieved through a Suzuki-Miyaura coupling. As compared to CA4, the derivative with a phenyl moiety has shown increased potency in its abi