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863504-84-1

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863504-84-1 Usage

General Description

Tert-butyl 3-aminopyrazole-l-carboxylate, also known by its chemical formula C9H16N4O2, is a synthetic organic compound with potential applications in chemical and pharmaceutical industries. It is a derivative of pyrazole, a five-membered heterocyclic ring containing two nitrogen atoms. The tert-butyl group provides steric hindrance, which can affect the compound's reactivity and stability. The presence of an amino group and a carboxylate group in the molecule suggests that it may have potential as a building block for the synthesis of other organic compounds or as a precursor for the development of pharmaceutical agents. Further research and analysis of its properties and potential applications are needed to fully understand and utilize the potential of tert-butyl 3-aminopyrazole-l-carboxylate.

Check Digit Verification of cas no

The CAS Registry Mumber 863504-84-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,3,5,0 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 863504-84:
(8*8)+(7*6)+(6*3)+(5*5)+(4*0)+(3*4)+(2*8)+(1*4)=181
181 % 10 = 1
So 863504-84-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H13N3O2/c1-8(2,3)13-7(12)11-5-4-6(9)10-11/h4-5H,1-3H3,(H2,9,10)

863504-84-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 3-aminopyrazole-1-carboxylate

1.2 Other means of identification

Product number -
Other names tert-Butyl 3-amino-1H-pyrazole-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:863504-84-1 SDS

863504-84-1Downstream Products

863504-84-1Relevant articles and documents

4-((1H-pyrazol-3-yl)amino)phthalazin-1(2H)-one derivatives and pharmaceutical composition for use in preventing or treating cancer containing the same as an active ingredient

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Paragraph 0203-0209, (2020/12/01)

The present invention relates to a 4-((1H-pyrazol-3-yl)amino)phthalazine-1(2H)-one derivative and a pharmaceutical composition for preventing or treating cancer containing the same as an active component. The derivative exhibits high inhibitory activity on various protein kinases, and in particular, has excellent inhibitory ability on RET proto-oncogene enzymes, and also has an excellent inhibitory effect on proliferation of medullary thyroid cancer cells and lung cancer cells expressing RET fusion genes, thereby being able to be usefully used for treating medullary thyroid cancer or lung cancer, and in particular, being able to be usefully used for treating cancer in which RET fusion genes are expressed.

Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands

Qian, Hai-Yan,Wang, Zhi-Long,Chen, Li-Li,Pan, You-Lu,Xie, Xiao-Yu,Xie, Xin,Chen, Jian-Zhong

supporting information, p. 2455 - 2463 (2018/11/23)

Herein we describe the design and synthesis of a new series of heteroarylpyrimidine/heteroaryltriazine derivatives on the basis of quinazoline-2,4(1H,3H)-diones as CB2R-selective ligands using a bioisosterism strategy. An acetamide group was explored to displace the enamine linker of the lead compound for the purpose of stereoisomerism elimination and hydrophilicity increase. As a result, some of the synthesized compounds showed high bioactivity and selectivity for CB2R in calcium mobilization assays, and four displayed CB2R agonist activity, with EC50 values below 30 nm. The compound exhibiting the highest agonist activity toward CB2R (EC50=7.53±3.15 nm) had a selectivity over CB1R of more than 1328-fold. Moreover, structure–activity relationship (SAR) studies indicated that the substituents on the nucleus play key roles in the functionality of a ligand, with one such example demonstrating CB2R antagonist activity. Additionally, molecular docking simulations were conducted with the aim of better understanding of these new derivatives in relation to the structural requirements for agonists/antagonists binding to CB2R.

PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME

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Paragraph 00301, (2017/06/12)

Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of, for example, pain.

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