863506-16-5 Usage
Chemical Family
2(1H)-Quinazolinone
Molecular Structure
Consists of a 2(1H)-quinazolinone core, a cyclopentyl group at the 8th position, a methoxy group at the 7th position, and a methyl group at the 5th position
Type of Compound
Cyclic organic compound
Pharmacological Properties
Known for its potential pharmacological properties
Therapeutic Agent
Has been studied as a potential therapeutic agent in the treatment of various medical conditions
Value in Medicinal Chemistry
Unique structural features make it a valuable compound for medicinal chemistry research and drug development
Check Digit Verification of cas no
The CAS Registry Mumber 863506-16-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,3,5,0 and 6 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 863506-16:
(8*8)+(7*6)+(6*3)+(5*5)+(4*0)+(3*6)+(2*1)+(1*6)=175
175 % 10 = 5
So 863506-16-5 is a valid CAS Registry Number.
863506-16-5Relevant articles and documents
2-Aminoquinazoline inhibitors of cyclin-dependent kinases
Bathini, Yadagiri,Singh, Inderjit,Harvey, Patricia J.,Keller, Paul R.,Singh, Rajeshwar,Micetich, Ronald G.,Fry, David W.,Dobrusin, Ellen M.,Toogood, Peter L.
, p. 3881 - 3885 (2005)
The inhibition of cyclin-dependent kinase 4 (Cdk4) causes cell cycle arrest and restores a checkpoint that is absent in the majority of tumor cells. Compounds that inhibit Cdk4 selectively are targeted for treating cancer. Appropriate substitution of 2-aminoquinazolines is demonstrated to produce high levels of selectivity for Cdk4 versus closely related serine-threonine kinases.
