863555-82-2Relevant academic research and scientific papers
Enantio- and diastereoselective construction of vicinal quaternary and tertiary carbon centers by catalytic Michael reaction of α-substituted β-keto esters to cyclic enones
Majima, Keisuke,Tosaki, Shin-Ya,Ohshima, Takashi,Shibasaki, Masakatsu
, p. 5377 - 5381 (2007/10/03)
A catalytic enantio- and diastereoselective Michael reaction was achieved to construct vicinal quaternary and tertiary carbon centers in one step. Using 5 mol % of La(O-i-Pr)3 and 10 mol % of a new N-linked-BINOL type ligand, the reaction of α-
