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Tert-butyl (2S)-2-[5-(benzylamino)-1H-tetrazol-1-yl]methyl-pyrrolidine-1-carboxylate, also known as Boc-pyroglutamyl-lysyl-tetrazole, is a synthetic peptide derivative characterized by its complex structure featuring a pyrrolidine ring, a tetrazole ring, and a benzylamino group. tert-butyl (2S)-2-[5-(benzylamino)-1H-tetrazol-1-yl]methyl-pyrrolidine-1-carboxylate is equipped with a tert-butyl group that acts as a protecting group for the amino acid residue, while the tetrazole ring may confer diverse biological activities. This multifunctional compound holds promise for applications in medicinal chemistry research and drug development due to its potential binding interactions with other molecules.

863671-66-3

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863671-66-3 Usage

Uses

Used in Medicinal Chemistry Research:
Tert-butyl (2S)-2-[5-(benzylamino)-1H-tetrazol-1-yl]methyl-pyrrolidine-1-carboxylate is used as a research compound for exploring its potential biological activities and interactions with other molecules. The presence of the tetrazole ring, which is known for its diverse applications in medicinal chemistry, makes tert-butyl (2S)-2-{[5-(benzylamino)-1H-tetrazol-1-yl]methyl}-pyrrolidine-1-carboxylate a valuable tool for studying its effects on various biological targets.
Used in Drug Development:
In the pharmaceutical industry, tert-butyl (2S)-2-[5-(benzylamino)-1H-tetrazol-1-yl]methyl-pyrrolidine-1-carboxylate is used as a lead compound for drug development. Its unique structure, including the lysine residue, suggests that it may have binding interactions with other molecules, which could be harnessed to create new therapeutic agents with specific targeting capabilities.
Used in Biochemical Studies:
Tert-butyl (2S)-2-[5-(benzylamino)-1H-tetrazol-1-yl]methyl-pyrrolidine-1-carboxylate is utilized as a probe in biochemical studies to investigate its binding properties and potential interactions with biological systems. Understanding these interactions can provide insights into the compound's mechanism of action and its suitability for various applications in biochemistry and molecular biology.

Check Digit Verification of cas no

The CAS Registry Mumber 863671-66-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,3,6,7 and 1 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 863671-66:
(8*8)+(7*6)+(6*3)+(5*6)+(4*7)+(3*1)+(2*6)+(1*6)=203
203 % 10 = 3
So 863671-66-3 is a valid CAS Registry Number.

863671-66-3Downstream Products

863671-66-3Relevant academic research and scientific papers

1-alkyl-5-((di)alkylamino) tetrazoles: Building blocks for peptide surrogates

Tymtsunik, Andriy V.,Bilenko, Vitaliy A.,Kokhan, Serhiy O.,Grygorenko, Oleksandr O.,Volochnyuk, Dmitriy M.,Komarov, Igor V.

experimental part, p. 1174 - 1180 (2012/03/12)

An approach to the synthesis of 1-alkyl-5-((di)alkylamino)tetrazoles by nucleophilic substitution in 1-alkyl-5-sulfonyltetrazoles with anions generated from the primary or secondary amines was developed. Tolerance of the method to the presence of some fun

Dimeric small molecule potentiators of apoptosis

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Page/Page column 32, (2008/06/13)

Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, dimeric Smac mimetic, and a resultant increase in apoptosis of the target cells is detected. The contacting step may be effected by administering to a pharmaceutical composition comprising a therapeutically effective amount of the dimeric mimetic, wherein the individual may be subject to concurrent or antecedent radiation or chemotherapy for treatment of a neoproliferative pathology.

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