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863671-84-5

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863671-84-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 863671-84-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,3,6,7 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 863671-84:
(8*8)+(7*6)+(6*3)+(5*6)+(4*7)+(3*1)+(2*8)+(1*4)=205
205 % 10 = 5
So 863671-84-5 is a valid CAS Registry Number.

863671-84-5Relevant articles and documents

Dimeric small molecule potentiators of apoptosis

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Page/Page column 35; 36; 38, (2008/06/13)

Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, dimeric Smac mimetic, and a resultant increase in apoptosis of the target cells is detected. The contacting step may be effected by administering to a pharmaceutical composition comprising a therapeutically effective amount of the dimeric mimetic, wherein the individual may be subject to concurrent or antecedent radiation or chemotherapy for treatment of a neoproliferative pathology.

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