863762-20-3

Basic information

• Product Name: 2,2-dimethylpropionic acid 7-chloro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester
• Synonyms: 2,2-dimethylpropionic acid 7-chloro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester
• CAS NO: 863762-20-3
• Molecular Weight: 444.915
• Mol File: 863762-20-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,2-dimethylpropionic acid 7-chloro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethylpropionic acid 7-chloro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester(863762-20-3)
• EPA Substance Registry System: 2,2-dimethylpropionic acid 7-chloro-1-(2-methyl-4-nitrobenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester(863762-20-3)

Safety Data

• Hazardous Substances Data: 863762-20-3(Hazardous Substances Data)

Upstream product

• 863762-02-1 2,2-dimethylpropionic acid 4-[(E)-hydroxyimino]-7-chloro-1,2,3,4-tetrahydronaphthalen-1-yl ester 
• 804498-94-0 (rac)-7-chloro-4-oxo-1,2,3,4-tetrahydronaphthalen-1-yl pivalate 
• 863762-10-1 2,2-dimethylpropionic acid 7-chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester 
• 30459-70-2 2-methyl-4-nitrobenzoyl chloride 

Downstream Products

• 150683-30-0 tolvaptan 
• 863762-24-7 2,2-dimethylpropionic acid 7-chloro-1-(4-amino-2-methylbenzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl ester 

Relevant articles and documents

Method of preparing benzazepines and derivatives thereof

The invention relates to a method of preparing benzazepine compounds having general formula (IA) consisting in reacting at least one compound having general formula (IIA) with an olefin, the compound thus obtained then being cyclised such as to produce tetralone, followed by the oxime derivative of same, which, by transformation by a Beckmann rearrangement, gives rise to the desired compounds.