863868-91-1Relevant articles and documents
Enantioselective Michael addition to α,β-unsaturated imides catalyzed by a bifunctional organocatalyst
Hoashi, Yasutaka,Okino, Tomotaka,Takemoto, Yoshiji
, p. 4032 - 4035 (2005)
(Chemical Equation Presented) High enantioselectivities (up to 94 % ee) were attained in the Michael addition of a variety of α,β-unsaturated imides 1 and malononitrile (2) catalyzed by bifunctional thiourea 4. The pyrrolidinone moiety of 1 plays a key ro