863868-94-4Relevant articles and documents
Design, synthesis, and application of chiral electron-poor guanidines as hydrogen-bonding catalysts for the Michael reaction
Thai, Karen,Gravel, Michel
experimental part, p. 751 - 755 (2010/07/17)
The first chiral electron-poor guanidine organocatalysts were synthesized. The presence of a tunable electron-withdrawing group on the guanidine moiety allows for the modulation of the catalysts' activity. The application of this new class of organocatalysts to the Michael reaction is demonstrated.