86388-87-6Relevant academic research and scientific papers
Regio- and stereoselective synthesis of 2-deoxy-C-aryl glycosides via palladium catalyzed decarboxylative reactions
Xiang, Shaohua,Cai, Shuting,Zeng, Jing,Liu, Xue-Wei
supporting information; experimental part, p. 4608 - 4611 (2011/10/13)
An efficient and versatile approach for the synthesis of 2-deoxy-C-aryl glycosides is reported. This strategy is based on a palladium-catalyzed decarboxylative Heck coupling reaction of benzoic acids and glycals. A wide variety of glycals and benzoic acid
Arylation de glycals catalysee par les sels de palladium: nouvelle synthese de C-glycosides
Czernecki, Stanislas,Dechavanne, Veronique
, p. 533 - 540 (2007/10/02)
The arylation of peracetylated glycals catalyzed by palladium salts provides a new synthesis of C-glycosides.The title reaction is applied to several aromatic compounds, including fluoro and nitro derivatives.The regioselectivity of the reaction with respect to the aromatic nucleus is explained by the formation of an arylpalladium directly from the aromatic compound and the salt.A two-step mechanism, involving syn-addition of the arylpalladium to the glycal double bond, followed by a syn-elimination is proposed and discussed.
