863886-50-4Relevant academic research and scientific papers
A mild synthesis of N-functionalised bromomaleimides, thiomaleimides and bromopyridazinediones
Casta?eda, Lourdes,Wright, Zo? V.F.,Marculescu, Cristina,Tran, Trang M.,Chudasama, Vijay,Maruani, Antoine,Hull, Elizabeth A.,Nunes, Jo?o P.M.,Fitzmaurice, Richard J.,Smith, Mark E.B.,Jones, Lyn H.,Caddick, Stephen,Baker, James R.
supporting information, p. 3493 - 3495 (2013/07/05)
Bromomaleimides are useful building blocks in synthesis and powerful reagents for the selective chemical modification of proteins. A mild new synthesis of these reagents is described, along with the convenient transferability of the approach to dithiomale
Development of antiproliferative phenylmaleimides that activate the unfolded protein response
Muus, Ulrike,Hose, Curtis,Yao, Wei,Kosakowska-Cholody, Teresa,Farnsworth, David,Dyba, Marzena,Lountos, George T.,Waugh, David S.,Monks, Anne,Burke Jr., Terrence R.,Michejda, Christopher J.
supporting information; experimental part, p. 4535 - 4541 (2010/08/22)
The current paper presents the synthesis and evaluation of a series of maleimides that were designed to inhibit the Cdc25 phosphatase by alkylation of catalytically essential cysteine residues. Although in HepB3 cell culture assays the analogues did exhib
Maleiimide anti-tumor phosphatase inhibitors
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Page/Page column 13, (2008/06/13)
The present invention features maleiimide compounds, pharmaceutical compositions of maleiimide compounds and methods of treating a patient suffering from cancer, the method comprising administering to a patient one or more maleiimide compounds of the inve
