86390-73-0

Basic information

• Product Name: N-<(3S,4S)-cis-1-(2,4-dimethoxybenzyl)-4-<(R)-2,2-dimethyl-1,3-dioxalan-4-yl>-2-oxo-3-azetidinyl>phthalimide
• Synonyms: N-<(3S,4S)-cis-1-(2,4-dimethoxybenzyl)-4-<(R)-2,2-dimethyl-1,3-dioxalan-4-yl>-2-oxo-3-azetidinyl>phthalimide
• CAS NO: 86390-73-0
• Molecular Weight: 466.491
• Mol File: 86390-73-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N-<(3S,4S)-cis-1-(2,4-dimethoxybenzyl)-4-<(R)-2,2-dimethyl-1,3-dioxalan-4-yl>-2-oxo-3-azetidinyl>phthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-<(3S,4S)-cis-1-(2,4-dimethoxybenzyl)-4-<(R)-2,2-dimethyl-1,3-dioxalan-4-yl>-2-oxo-3-azetidinyl>phthalimide(86390-73-0)
• EPA Substance Registry System: N-<(3S,4S)-cis-1-(2,4-dimethoxybenzyl)-4-<(R)-2,2-dimethyl-1,3-dioxalan-4-yl>-2-oxo-3-azetidinyl>phthalimide(86390-73-0)

Safety Data

• Hazardous Substances Data: 86390-73-0(Hazardous Substances Data)

Upstream product

• 1089691-24-6 phthaloylglycine acid chloride 
• 20781-20-8 2,4-Dimethoxybenzylamine 
• 7487-88-9 magnesium sulfate 
• 6780-38-7 N-phthaloylglycine chloride 
• 56710-46-4 L-5,6-isopropylidene-gulono-1,4-lactone 
• 22323-80-4 (4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 88852-09-9 (R,E)-1-(2,4-dimethoxyphenyl)-N-((2,2-dimethyl-1,3-dioxolan-4-yl)methylene)methanamine 

Downstream Products

• 86334-63-6 (3S,4S)-3-(benzyloxycarboxamido)-1-(2,4-dimethoxybenzyl)-4-(hydroxymethyl)-2-azetidinone 

Relevant articles and documents

Process Development for the Synthesis of a Monobactam Antibiotic-LYS228

A scalable process for the novel monobactam antibiotic LYS228 has been developed. This paper covers a novel scalable process for producing β-lactam 10 in the multiple kilogram scale. An alternative approach to compound 7 without protecting-group exchange

MONOBACTAM ORGANIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS

This invention pertains generally to antibacterial compounds of Formula I, as further described herein, and pharmaceutically acceptable salts and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds to treat infections such as those caused by Gram-negative bacteria.

A Convenient Synthesis of L-(S)-Glyceraldehyde Acetonide from L-Ascorbic Acid

L-(S)-glyceraldehyde acetonide is easily obtained from L-ascorbic acid by three-step procedure.Since the aldehyde is rather unstable in pure form it is more convenient to use it as an aqueous solution.It was used to synthesize L-(R)-glycerol acetonide, monocyclic-β-lactams, and olefins (by Wittig reaction).