86390-77-4 Usage
Uses
Different sources of media describe the Uses of 86390-77-4 differently. You can refer to the following data:
1. Activator of phospholipid-dependent protein kinase C; and stimulator of secretion and aggregation in blood platelets
2. Activator of phospholipid-dependent protein kinase C; and stimulator of secretion and aggregation in blood platelets.x
3. 18:1-2:0 DG (1-oleoyl-2-acetyl-sn-glycerol) has been used as a diacyl glycerol (DAG) analog to test its impact on DAG-sensitive channels in thalamocortical (TC) neurons. It may be used as an internal standard for retention time calibration in ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF MS)?for blood sample lipid quantification. It may also be used as a protein kinase C (PKC) activator in adrenal glands.
General Description
18:1-2:0 DG, also called 1-oleoyl-2-acetyl-sn-glycerol (OADG), is a synthetic analog of diacyl glycerol (DAG) and is membrane permeable.
Biochem/physiol Actions
1-Oleoyl-2-acetyl-sn-glycerol is a synthetic, cell permeable diacylglycerol analog. It is often used as an activator of calcium-dependent protein kinase C (PKC).
Check Digit Verification of cas no
The CAS Registry Mumber 86390-77-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,3,9 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 86390-77:
(7*8)+(6*6)+(5*3)+(4*9)+(3*0)+(2*7)+(1*7)=164
164 % 10 = 4
So 86390-77-4 is a valid CAS Registry Number.
InChI:InChI=1/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)27-20-22(19-24)28-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10-/t22-/m0/s1
86390-77-4Relevant articles and documents
O-Silylated C3-halohydrins as a novel class of protected building blocks for total, regio- and stereocontrolled synthesis of glycerolipid frameworks
Stamatov, Stephan D.,Stawinski, Jacek
experimental part, p. 463 - 477 (2010/02/16)
We propose O-silylated C3-halohydrins [1(3)-O-silyl-2-O-acyl-, 1,2(2,3)-O-bis(silyl)-, and 1(3)-O-acyl-2-O-silyl-3(1)-halo-sn-glycerides] as new chirons in the total synthesis of glycerolipid constructs. These are efficiently producible via opening of the
A direct transformation of O-silyl groups into O-trichloroacetates. A novel synthetic approach to protein kinase C ligands: 1-Oleoyl-2-acetyl- and 1-hexadecyl-2-acetyl-sn-glycerols
Stamatov, Stephan D.,Kullberg, Martin,Stawinski, Jacek
, p. 6855 - 6859 (2007/10/03)
A fluoride ion-promoted direct esterification of tert-butyldimethylsilyl- (TBDMS), or triisopropylsilyl (TIPS)-protected glycerol derivatives by means of trichloroacetic anhydride (TCAA), followed by removal of the trichloroacetyl transient protection, provides a new, efficient entry to stereochemically pure 1-oleoyl-2-acetyl- and 1-O-hexadecyl-2-acetyl-sn-glycerols.
COSMETIC COMPOSITION
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, (2008/06/13)
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