863970-07-4

Upstream product

• 123-38-6 propionaldehyde 
• 104464-03-1 1,1-dibromo-2-(2-methylphenyl)ethene 
• 766-47-2 1-ethynyl-2-methylbenzene 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 863970-09-6 (E)-1-(2-tolyl)pent-1-en-3-one 
• 1346155-44-9 1-o-tolylpent-1-yn-3-yl benzoate 
• 1346155-73-4 1-ethyl-4-methyl-1H-inden-3-yl benzoate 

Relevant academic research and scientific papers

PtI2-Catalyzed tandem 3,3-rearrangement/Nazarov reaction of arylpropargylic esters: Synthesis of indanone derivatives

An efficient PtI2-catalyzed tandem reaction of arylpropargylic esters, involving 3,3-rearrangement and Nazarov reaction, has been developed to produce 3-substituted and 3,3-disubstituted indanone derivatives. This approach provided a pathway to the synthesis of indanone skeletons in natural products.

Cationic rhodium(I)/BINAP complex-catalyzed isomerization of secondary propargylic alcohols to α,β-enones

(Chemical Equation Presented) We have developed a cationic rhodium(I)/BINAP complex-catalyzed isomerization of secondary propargylic alcohols to α,β-enones. The asymmetric variant of this reaction, a kinetic resolution of secondary propargylic alcohols, was also developed with good selectivity. The mechanistic study revealed that the isomerization proceeds through intramolecular 1,3- and 1,2-hydrogen migration pathways.