86398-50-7Relevant academic research and scientific papers
Transformations of resin-bound pyridinium ylides: I. A stereoselective synthesis of 2,2,3-trisubstituted cyclopropanecarboxylates
Vo, Nha Huu,Eyermann, Charles Joseph,Hodge, C. Nicholas
, p. 7951 - 7954 (1997)
Trans-3-alkyl- or -arylcyclopropanecarboxylates, substituted in the 2-position with alkoxycarbonyl or nitrile groups, are efficiently prepared by coupling bromoacetic acid with Wang resin followed by pyridinium ylide formation and condensation of the ylide with ethylidene malonate derivatives. Good yields are obtained after cleaving the resin and esterifying the resulting cyclopropanecarboxylic acid with diazomethane.
THE INFLUENCE OF THE Π-ELECTRON DISTRIBUTION AND Π-BOND STABILITY OF KETENE ACETALS ON THEIR REACTIVITY AND STEREOSELECTIVITY IN THERMAL (2+2) CYCLOADDITIONS WITH 1,1-DICYANOSTYRENES
Scheeren, Hans W.,Rossum,Anton J. R. van,Nivard, Rutger J. F.
, p. 1345 - 1354 (2007/10/02)
The reactions of series of ketene acetals (R1R2C=C(OMe)2) with dicyanostyrenes (ArCH=C(CN)2) have been studied.Ketene acetals with a symmetrical Π-electron distribution give stable cyclobutanes via reactions in which no dipolar inter
