863988-84-5

Upstream product

• 863988-81-2 (2R,4S)-1-(benzyloxy)-6-(tert-butyldiphenylsilyloxy)hexane-2,4-diol 
• 77-76-9 2,2-dimethoxy-propane 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 81096-96-0 (3S,5R)-6-Benzyloxy-hexane-1,3,5-triol 

Downstream Products

• 863921-95-3 (2Z,4E,8E,10Z)-(S)-7-(tert-Butyl-dimethyl-silanyloxy)-12-{(4S,6R)-6-[(1E,3E)-(R)-8-(4-methoxy-benzyloxy)-nona-1,3-dienyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-dodeca-2,4,8,10-tetraenoic acid ethyl ester 
• 863921-91-9 (2-{(4S,6R)-6-[(1E,3E)-(R)-6-Benzenesulfonyl-8-(4-methoxy-benzyloxy)-nona-1,3-dienyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethoxy)-tert-butyl-diphenyl-silane 
• 863921-92-0 tert-Butyl-(2-{(4S,6R)-6-[(1E,3E)-(R)-8-(4-methoxy-benzyloxy)-nona-1,3-dienyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethoxy)-diphenyl-silane 
• 863921-90-8 {2-[(4S,6R)-6-((1E,3E)-5-Bromo-penta-1,3-dienyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethoxy}-tert-butyl-diphenyl-silane 
• 863921-89-5 (2E,4E)-5-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-penta-2,4-dien-1-ol 
• 863921-94-2 (4R,6R)-4-(2-Iodo-ethyl)-6-[(1E,3E)-(R)-8-(4-methoxy-benzyloxy)-nona-1,3-dienyl]-2,2-dimethyl-[1,3]dioxane 
• 863921-93-1 2-{(4S,6R)-6-[(1E,3E)-(R)-8-(4-Methoxy-benzyloxy)-nona-1,3-dienyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethanol 
• 863921-70-4 (4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde 
• 863921-87-3 {(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-methanol 

Relevant academic research and scientific papers

A convergent and stereoselective synthesis of a seco-precursor of macrolactin A

A seco-precursor of macrolactin A was synthesized by coupling two advanced segments. Wittig reaction and Horner-Emmons reaction were utilized to construct the three characteristic E,Z and E,E dienes. The C1-C10 segment was synthesize

Synthesis of a sec-precursor and analogues of macrolactin A

(Chemical Equation Presented) A highly convergent and efficient route to sec-precursor 26 of macrolactin A has been developed. In the synthesis, Wittig and Horner-Emmons reactions were utilized to construct the conjugated dienes and control the right conf