863997-72-2Relevant articles and documents
TOTAL SYNTHESIS OF TRIOXACARCIN DC-45-A2 AND PREPARATION OF TRIOXACARCIN ANALOGS
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Page/Page column 85; 86; 96; 97; 98, (2016/07/05)
In one aspect, the present invention provides novel derivatives of trioxacarin analogs of the formula (I) wherein the variables are as defined herein. The application also provides compositions, methods of treatment, and methods of synthesis thereof.
Total synthesis of trioxacarcin DC-45-A2
Nicolaou, K. C.,Cai, Quan,Qin, Bo,Petersen, Mette T.,Mikkelsen, Remi J. T.,Heretsch, Philipp
, p. 3074 - 3078 (2015/07/01)
An enantioselective total synthesis of trioxacarcin DC-45-A2 (1) featuring a novel Lewis acid-induced cascade rearrangement of epoxyketone 6 to forge the polyoxygenated 2,7-dioxabicyclo[2.2.1]heptane core of the molecule is described.
TRIOXACARCINS AND USES THEREOF
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, (2011/10/13)
The present invention relates to trioxacarcin compounds of the formula: (I) or pharmaceutically acceptable forms thereof; wherein R1, R2, R3, R4, R5, R6, R7, R8, and R9 are as defined herein. The present invention also provides processes for preparing such compounds and intermediates thereto; pharmaceutical compositions comprising such compounds; and methods of use and treatment.
Fluorescence study on the nyctinasty of Phyllanthus urinaria L. using novel fluorescence-labeled probe compounds
Kato, Nobuki,Inada, Masayoshi,Sato, Hirotaka,Miyatake, Ryoji,Kumagai, Tsutomu,Ueda, Minoru
, p. 7307 - 7318 (2007/10/03)
We report the synthesis of fluorescence-labeled probes based on phyllanthurinolactone 1, which is a leaf-closing substance of Phyllanthus urinaria L. The fluorescence study using biologically active probe 2 and inactive probes (epi-2 and 31) revealed that
Direct observation of a target cell of the leaf-closing factor by using novel fluorescence-labeled phyllanthurinolactone
Sato, Hirotaka,Inada, Masayoshi,Sugimoto, Takanori,Kato, Nobuki,Ueda, Minoru
, p. 5537 - 5541 (2007/10/03)
We report the synthesis of the fluorescence-labeled probe 2 based on phyllanthurinolactone 1, which is a leaf-closing substance of Phyllanthus urinaria L. Bioorganic studies using probe 2 showed leaf-closing activity at 1 × 10-5 M, which was on