86402-39-3

Basic information

• Product Name: 9-(1,3-benzodioxol-5-yl)-6,7-dimethoxy-1-oxo-1,3-dihydronaphtho[2,3-c]furan-4-yl 2-O-beta-D-glucopyranosyl-3,4-di-O-methyl-beta-D-xylopyranoside
• Synonyms: Naphtho(2,3-c)furan-1(3H)-one, 9-(1,3-benzodioxol-5-yl)-4-((2-O-beta-D-glucopyranosyl-3,4-di-O-methyl-beta-D-xylopyranosyl)oxy)-6,7-dimethoxy-
• CAS NO: 86402-39-3
• Molecular Formula: C₃₄H₃₈O₁₆
• Molecular Weight: 702.6559
• Mol File: 86402-39-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 930.3°C at 760 mmHg
• Flash Point: 295.1°C
• Density: 1.54g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.669
• CAS DataBase Reference: 9-(1,3-benzodioxol-5-yl)-6,7-dimethoxy-1-oxo-1,3-dihydronaphtho[2,3-c]furan-4-yl 2-O-beta-D-glucopyranosyl-3,4-di-O-methyl-beta-D-xylopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(1,3-benzodioxol-5-yl)-6,7-dimethoxy-1-oxo-1,3-dihydronaphtho[2,3-c]furan-4-yl 2-O-beta-D-glucopyranosyl-3,4-di-O-methyl-beta-D-xylopyranoside(86402-39-3)
• EPA Substance Registry System: 9-(1,3-benzodioxol-5-yl)-6,7-dimethoxy-1-oxo-1,3-dihydronaphtho[2,3-c]furan-4-yl 2-O-beta-D-glucopyranosyl-3,4-di-O-methyl-beta-D-xylopyranoside(86402-39-3)

Safety Data

• Hazardous Substances Data: 86402-39-3(Hazardous Substances Data)

Upstream product

• 86520-63-0 2,3,4,6-tetra-O-acetyl-α-galactopyranosyl trichloroacetimidate 
• 141839-43-2 glucopyranosyl trichloroacetimidate 

Relevant articles and documents

Synthesis and Evaluation of Cleistanthin A Derivatives as Potent Vacuolar H+-ATPase Inhibitors

Twelve new glycosides and alkane derivatives of cleistanthin A were designed and synthesized. Their in vitro antiproliferative activity was investigated against HCT-116, HepG2, A549, Hela tumor cell lines and HEK293 cell by MTT assay. Most of these compounds displayed antiproliferative effects on four cancer cells at submicromolar concentration, but they were less potent than cleistanthin A Moreover, they showed no antiproliferative effects on HEK293 cell at 200 nm. The most potent compounds, 3e and 4a, have been shown to inhibit the activity of vacuolar H+-ATPase (V-ATPase) and neutralize the pH of lysosomes at submicromolar concentrations.