864064-32-4

Upstream product

• 189366-37-8 (1R,3R,4S)-4-(tert-butyldimethylsiloxy)-1-hydroxy-5-oxocyclohexane-1,3-carbolactone 
• 77-95-2 D-(-)-quinic acid 
• 863983-59-9 methyl (1S,3R,4S,5S,6S)-6-chloro-1,3-dihydroxy-4,5-(isopropylidenedioxy)cyclohexanecarboxylate 
• 863983-60-2 methyl (1S,4R,5S,6S)-6-chloro-1-hydroxy-4,5-(isopropylidenedioxy)-3-oxocyclohexanecarboxylate 
• 863983-61-3 methyl (1S,4R,5S,6S)-6-chloro-1,4,5-trihydroxy-3-oxocyclohexanecarboxylate 
• 863983-58-8 (1S,3R,4R,5S,6S)-6-chloro-1-hydroxy-4,5-(isopropylidenedioxy)cyclohexane-1,3-carbolactone 
• 863983-57-7 (1S,3R,4R,5S,6S)-6-chloro-1,4,5-trihydroxycyclohexane-1,3-carbolactone 
• 868526-03-8 (1R,4S,5R)-1,4-Dihydroxy-6-oxa-bicyclo[3.2.1]octane-3,7-dione 
• 863983-64-6 methyl (4R,5S,6R)-6-chloro-4,5-dihydroxy-3-oxocyclohex-1-enecarboxylate 
• 863983-62-4 methyl (1S,4R,5S,6S)-6-chloro-1-hydroxy-4,5-bis(trimethylsiloxy)-3-oxocyclohexanecarboxylate 
• 863983-63-5 methyl (4R,5S,6R)-6-chloro-4,5-bis(trimethylsiloxy)-3-oxocyclohex-1-enecarboxylate 
• 863983-55-5 (1S,3R,4S,6R)-4-(tert-butyldimethylsiloxy)-6-chloro-1-hydroxy-5-oxocyclohexane-1,3-carbolactone 
• 863983-56-6 (1S,3R,4R,5S,6S)-4-(tert-butyldimethylsiloxy)-6-chloro-1,5-dihydroxycyclohexane-1,3-carbolactone 

Relevant academic research and scientific papers

Stereoselective syntheses of diastereomers of antitumor natural product pericosine A from (-)-quinic acid

The stereoselective syntheses of diastereomers of antitumor natural pericosine A from (-)-quinic acid were achieved. One of the diastereomers, methyl (3R,4S,5S,6R)-6-chloro-3,4,5-trihydroxycyclohex-1-enecarboxylate, possesses the reported structure of per

Synthetic study toward antitumour natural product pericosine A

The stereoselective total synthesis of methyl (3R,4S,5S,6R)-6-chloro-3,4,5- trihydroxy-1-cyclohex-1-enecarboxylate (1), which had been reported as the antitumour marine natural product pericosine A, from (-)-quinic acid was achieved. From the total synthesis, it was confirmed that the reported stereostructure of pericosine A was incorrect because the spectroscopic data of the synthetic product were not identical with those of the natural compound. Copyright