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864073-42-7

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864073-42-7 Usage

Uses

12-AMino Minocycline is an impurity of Minocycline (M344800),it is used in the preparation of calpain inhibitors.

Check Digit Verification of cas no

The CAS Registry Mumber 864073-42-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,4,0,7 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 864073-42:
(8*8)+(7*6)+(6*4)+(5*0)+(4*7)+(3*3)+(2*4)+(1*2)=177
177 % 10 = 7
So 864073-42-7 is a valid CAS Registry Number.

864073-42-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (4S,4aS,5aR,12aS)-12-amino-4,7-bis(dimethylamino)-1,10,12a-trihydroxy-3,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide

1.2 Other means of identification

Product number -
Other names 12-Amino Minocycline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:864073-42-7 SDS

864073-42-7Upstream product

864073-42-7Downstream Products

864073-42-7Relevant articles and documents

TETRACYCLINES AND THEIR USE AS CALPAIN INHIBITORS

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Page/Page column 60-61, (2010/02/13)

Tetracyclines are useful as calpain inhibitors, particularly inhibitors of calpain I and II, as demonstrated in enzymatic assays as well as at the cellular and animal levels. Tetracyclines may be used in the treatment of a wide range of conditions implicated by or associated with calpain activity or activation, including cellular protection from apoptosis and necrosis, particularly n eu ro protection, prevention of cell motility (e.g. anti-metastasis of cancer) and treatment of certain infectious diseases (e.g. malaria and AIDS). Some tetracyclines are particularly useful as calpain inhibitors since they are also antioxidants, oxidative stress often being associated with conditions where calpain is activated.

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