86428-58-2

Basic information

• Product Name: (-) N (methyl-3 cyclohexylidene) hexylamine
• CAS NO: 86428-58-2
• Molecular Weight: 195.348
• Mol File: 86428-58-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-) N (methyl-3 cyclohexylidene) hexylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (-) N (methyl-3 cyclohexylidene) hexylamine(86428-58-2)
• EPA Substance Registry System: (-) N (methyl-3 cyclohexylidene) hexylamine(86428-58-2)

Safety Data

• Hazardous Substances Data: 86428-58-2(Hazardous Substances Data)

Upstream product

• 111-26-2 hexan-1-amine 
• 13368-65-5 (3R)-3-methylcyclohexanone 

Downstream Products

• 38615-92-8 (-) methyl-3 cyclohexilidene malonitrile 

Relevant articles and documents

CINETIQUE ET MECANISME DE LA REACTION DE KNOEVENAGEL DANS LE BENZENE-2 REACTION DU MALONITRILE ET DE LA (+) METHYL-3 CYCLOHEXANONE EN PRESENCE D'UNE AMINE PRIMARIE PURE ET DE SON MELANGE AVEC L'ACIDE ACETIQUE

The kinetics of the reaction of (+)-3-methyl cyclohexanone with malonitrile were studied in benzene at 25 deg C, in the presence of hexylamine-acetic acid mixtures.Hexylamine gives an imine with cyclohexanone in an acid-catalyzed step.This imine then reacts quickly with malononitrile.A rate law of zero order in malononitrile is observed.Separate kinetic results obtained for the formation of the imine and for the imine-malonitrile reaction support this mechanism.Without acetic acid, a complex rate law is observed; hexylamine acts mainly as a basic catalyst.Primary amine-carboxylic acid was used as a catalyst in Knoevenagel reaction, often giving an increase in yield and a diminution in the reaction time compared with the more commonly used catalysts: piperidine, β-alanine, AcOH-AcONH4.