864293-60-7

Upstream product

• 57946-56-2 2-fluoro-4-chloroaniline 
• 864293-49-2 methyl 2,4-dichloro-6-methoxyquinazoline-7-carboxylate 
• 1202899-27-1 2-chloro-4-[(4-chloro-2-fluorophenyl)amino]-6-methoxyquinazoline-7-carboxylic acid 

Downstream Products

• 864293-61-8 2-chloro-4-[(4-chloro-2-fluorophenyl)amino]-6-methoxyquinazoline-7-carbonitrile 

Relevant academic research and scientific papers

QUINAZOLINE DERIVATIVES

A compound useful as a preventive or a remedy for inflammatory diseases, allergic diseases or autoimmune diseases in which CC chemokine receptor 4 (CCR4) participates, i.e., a quinazoline derivative having an anilino or cycloalkylamino group at the 4-position and a cyclic amino group substituted by a nitrogen-containing heterocyclic group or an amino group via carbonyl such as piperazino at the 2-position. Because of having a favorable activity as a CCR4 function controller, the above-described compound is useful as a remedy or a preventive for inflammatory diseases, allergic diseases or autoimmune diseases, in particular, dermatitis, etc.