864366-90-5

Upstream product

• 111060-65-2 (S)-2-(dibenzylamino)-4-methylpentanal 
• 864366-74-5 (2S)-2-[(1S,2S)-1-(tert-butyl-dimethyl-silanyloxy)-2-dibenzylamino-4-methyl-pentyl]-(1S)-1-[1,3]dithian-2-yl-butane-1,4-diol 
• 864366-80-3 (3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid butylamide 
• 864366-75-6 (S)-dibenzyl-[(3S)-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-(2-[1,3]dithian-2-yl-tetrahydrofuran-3-yl)-methyl]-3-methyl-butyl]-amine 
• 864366-79-0 (3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2R)-2-carboxylic acid 
• 864366-78-9 (3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carboxylic acid 
• 864366-77-8 (3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carboxylic acid methyl ester 
• 864366-73-4 (3S)-3-[(1S,2S)-1-(tert-butyl-dimethyl-silanyloxy)-2-dibenzylamino-4-methyl-pentyl]-dihydro-furan-2-one 
• 864366-76-7 (3S)-3-[(1S)-1-(tert-butyl-dimethyl-silanyloxy)-(2S)-2-dibenzylamino-4-methyl-pentyl]-tetrahydro-furan-(2S)-2-carbaldehyde 
• 864366-87-0 (3S)-3-[(1S)-1-hydroxy-(2S)-2-tert-butoxycarbonylamino]-tetrahydro-furan-(2R)-2-carboxylic acid butylamide 
• 864366-56-3 (3R)-3-[(1S,2S)-2-dibenzylamino-1-hydroxy-4-methyl-pentyl]-dihydro-furan-2-one 
• 864366-58-5 (3S)-3-[(1S,2S)-2-dibenzylamino-1-hydroxy-4-methyl-pentyl]-dihydro-furan-2-one 

Relevant academic research and scientific papers

Stereoselective synthesis of constrained oxacyclic hydroxyethylene isosteres of aspartic protease inhibitors: Aldol and Mukaiyama aldol methodologies for branched tetrahydrofuran 2-carboxylic acids

The synthesis of diastereomeric 3-substituted-tetrahydrofuran 2-carboxylic acids in enantiopure form was achieved relying on aldol condensations of N-substituted α-amino aldehydes with enolates and enol silyl ethers of γ-butyrolactone. Catalytic YbFOD lea