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864445-41-0

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864445-41-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 864445-41-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,4,4,4 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 864445-41:
(8*8)+(7*6)+(6*4)+(5*4)+(4*4)+(3*5)+(2*4)+(1*1)=190
190 % 10 = 0
So 864445-41-0 is a valid CAS Registry Number.

864445-41-0Downstream Products

864445-41-0Relevant articles and documents

1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles

Huffman, John W.,Szklennik, Paul V.,Almond, Amanda,Bushell, Kristen,Selley, Dana E.,He, Hengjun,Cassidy, Michael P.,Wiley, Jenny L.,Martin, Billy R.

, p. 4110 - 4113 (2007/10/03)

A new class of cannabimimetic indoles, with 3-phenylacetyl or substituted 3-phenylacetyl substituents, has been prepared and their affinities for the cannabinoid CB1 and CB2 receptors have been determined. In general those compounds with a 2-substituted phenylacetyl group have good affinity for both receptors. The 4-substituted analogs have little affinity for either receptor, while the 3-substituted compounds are intermediate in their affinities. Two of these compounds, 1-pentyl-3-(2-methylphenylacetyl)indole (JWH-251) and 1-pentyl-3-(3-methoxyphenylacetyl)indole (JWH-302), have 5-fold selectivity for the CB1 receptor with modest affinity for the CB 2 receptor. GTPγS determinations indicate that both compounds are highly efficacious agonists at the CB1 receptor and partial agonists at the CB2 receptor.

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