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864445-60-3

864445-60-3

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864445-60-3 Usage

Uses

JWH-249, is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 8.4 and 20 nM, respectively). Synthetic Cannabinoids

Check Digit Verification of cas no

The CAS Registry Mumber 864445-60-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,4,4,4 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 864445-60:
(8*8)+(7*6)+(6*4)+(5*4)+(4*4)+(3*5)+(2*6)+(1*0)=193
193 % 10 = 3
So 864445-60-3 is a valid CAS Registry Number.

864445-60-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2-bromophenyl)-1-(1-pentylindol-3-yl)ethanone

1.2 Other means of identification

Product number -
Other names JWH-249

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:864445-60-3 SDS

864445-60-3Downstream Products

864445-60-3Relevant articles and documents

1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles

Huffman, John W.,Szklennik, Paul V.,Almond, Amanda,Bushell, Kristen,Selley, Dana E.,He, Hengjun,Cassidy, Michael P.,Wiley, Jenny L.,Martin, Billy R.

, p. 4110 - 4113 (2007/10/03)

A new class of cannabimimetic indoles, with 3-phenylacetyl or substituted 3-phenylacetyl substituents, has been prepared and their affinities for the cannabinoid CB1 and CB2 receptors have been determined. In general those compounds with a 2-substituted phenylacetyl group have good affinity for both receptors. The 4-substituted analogs have little affinity for either receptor, while the 3-substituted compounds are intermediate in their affinities. Two of these compounds, 1-pentyl-3-(2-methylphenylacetyl)indole (JWH-251) and 1-pentyl-3-(3-methoxyphenylacetyl)indole (JWH-302), have 5-fold selectivity for the CB1 receptor with modest affinity for the CB 2 receptor. GTPγS determinations indicate that both compounds are highly efficacious agonists at the CB1 receptor and partial agonists at the CB2 receptor.