86448-22-8

Basic information

• Product Name: [2-((1R,4R)-7-Acetyl-2-aza-bicyclo[2.2.2]oct-5-en-2-yl)-4-oxo-cyclohex-2-enyl]-acetic acid tert-butyl ester
• CAS NO: 86448-22-8
• Molecular Weight: 359.466
• Mol File: 86448-22-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-((1R,4R)-7-Acetyl-2-aza-bicyclo[2.2.2]oct-5-en-2-yl)-4-oxo-cyclohex-2-enyl]-acetic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-((1R,4R)-7-Acetyl-2-aza-bicyclo[2.2.2]oct-5-en-2-yl)-4-oxo-cyclohex-2-enyl]-acetic acid tert-butyl ester(86448-22-8)
• EPA Substance Registry System: [2-((1R,4R)-7-Acetyl-2-aza-bicyclo[2.2.2]oct-5-en-2-yl)-4-oxo-cyclohex-2-enyl]-acetic acid tert-butyl ester(86448-22-8)

Safety Data

• Hazardous Substances Data: 86448-22-8(Hazardous Substances Data)

Upstream product

• 5292-43-3 bromoacetic acid tert-butyl ester 
• 66531-20-2 3-[(1S,4S)-7-(2-Methyl-[1,3]dioxolan-2-yl)-2-aza-bicyclo[2.2.2]oct-5-en-2-yl]-cyclohex-2-enone 
• 86448-19-3 {2-[(1S,4S)-7-(2-Methyl-[1,3]dioxolan-2-yl)-2-aza-bicyclo[2.2.2]oct-5-en-2-yl]-4-oxo-cyclohex-2-enyl}-acetic acid tert-butyl ester 

Relevant articles and documents

MECHANISTIC AND SYNTHETIC ASPECTS OF THE ACID-CATALYZED AMINO-CLAISEN REARRANGEMENT OF N-(β-KETOVINYL)ISOQUINUCLIDENES.

Srudies of the acid-catalyzed, amino-Claisen rearrangement of N-(β-cyclohexenonyl)isoquinuclidines have provided results which pertain to the mechanism of the process and to synthetic applications for construction of the lycorane tetracyclic skeleton.