86453-45-4

Upstream product

• 2179-89-7 bis(1,3-diphenyl-2-imidazolidinylidene) 
• 122-51-0 orthoformic acid triethyl ester 
• 150-61-8 N,N'-diphenylethylenediamine 
• 88734-24-1 2,2'-Diselenobis(1,3-diphenyl-2-imidazolinium)-bis(trifluormethansulfonat) 
• 53316-26-0 <1,3-Diphenylimidazolidinium>-carbodithioat 

Downstream Products

• 88734-24-1 2,2'-Diselenobis(1,3-diphenyl-2-imidazolinium)-bis(trifluormethansulfonat) 
• 28639-60-3 1,1',3,3'-Tetraphenyl-2,4'-spirobiimidazolidin-2',5'-dion 
• 86453-49-8 1,2,2,3-Tetraphenylimidazolidin 
• 2513-64-6 1,3-diphenylimidazolidine 
• 86453-48-7 1,3-bis(4-bromophenyl)imidazolidin-2-one 
• 86453-47-6 2-(Bromseleno)-1,3-diphenylimidazolinium-bromid 
• 86453-46-5 1,3-Diphenylimidazolinium-iodid 
• 882-33-7 diphenyldisulfane 
• 150-61-8 N,N'-diphenylethylenediamine 

Relevant academic research and scientific papers

Synthesis and reactivity of subvalent compounds. Part 13: Reaction of triethyl orthoformate with amines and selenium - A convenient one-step three-component synthesis for selenoureas

Selenoureas are obtained by a novel three-component condensation reaction from metallic selenium, triethyl orthoformate and a primary or secondary amine. The reaction is carried out as solvent-free one pot-procedure at 180-190°C under inert gas with a reaction time of 8 h. The reaction was tested for piperidine, isopropylamine, N,N′-dimethylpropylenediamine (Me-NH-CH2-CH2-CH2-NH-Me) and N,N′-disubstituted ethylenediamines (R-NH-CH2-CH2-NH-R, R=Me, Et, iPr, tBu, Ph).

Use of sulfur and selenium compounds as precursors to nanostructured materials

The presently disclosed subject matter provides processes for preparing nanocrystals, including processes for preparing core-shell nanocrystals. The presently disclosed subject matter also provides sulfur and selenium compounds as precursors to nanostructured materials. The presently disclosed subject matter also provides nanocrystals having a particular particle size distribution.

Precursor reaction kinetics control compositional grading and size of CdSe1-: XSx nanocrystal heterostructures

We report a method to control the composition and microstructure of CdSe1-xSx nanocrystals by the simultaneous injection of sulfide and selenide precursors into a solution of cadmium oleate and oleic acid at 240 °C. Pairs of substituted thio- and selenoureas were selected from a library of compounds with conversion reaction reactivity exponents (kE) spanning 1.3 × 10-5 s-1 to 2.0 × 10-1 s-1. Depending on the relative reactivity (kSe/kS), core/shell and alloyed architectures were obtained. Growth of a thick outer CdS shell using a syringe pump method provides gram quantities of brightly photoluminescent quantum dots (PLQY = 67 to 90%) in a single reaction vessel. Kinetics simulations predict that relative precursor reactivity ratios of less than 10 result in alloyed compositions, while larger reactivity differences lead to abrupt interfaces. CdSe1-xSx alloys (kSe/kS = 2.4) display two longitudinal optical phonon modes with composition dependent frequencies characteristic of the alloy microstructure. When one precursor is more reactive than the other, its conversion reactivity and mole fraction control the number of nuclei, the final nanocrystal size at full conversion, and the elemental composition. The utility of controlled reactivity for adjusting alloy microstructure is discussed.

Inhibition of lactoperoxidase-catalyzed oxidation by imidazole-based thiones and selones: A mechanistic study

Herein, we describe the synthesis and biomimetic activity of a series of N,N-disubstituted thiones and selones that contain an imidazole pharmacophore. The N,N-disubstituted thiones do not show any inhibitory activity towards LPO-catalyzed oxidation reactions, but their corresponding N,N-disubstituted selones exhibit inhibitory activity towards LPO-catalyzed oxidation reactions. Substituents on the N atom of the imidazole ring appear to have a significant effect on the inhibition of LPO-catalyzed oxidation and iodination reactions. Selones 16, 17, and 19, which contain methyl, ethyl, and benzyl substituents, exhibit similar inhibition activities towards LPO-catalyzed oxidation reactions with IC50 values of 24.4, 22.5, and 22.5 μM, respectively. However, their activities are almost three-fold lower than that of the commonly used anti-thyroid drug methimazole (MMI). In contrast, selone 21, which contains a N-CH2CH2OH substituent, exhibits high inhibitory activity, with an IC50 value of 7.2 μM, which is similar to that of MMI. The inhibitory activity of these selones towards LPO-catalyzed oxidation/iodination reactions is due to their ability to decrease the concentrations of the co-substrates (H2O2 and I 2), either by catalytically reducing H2O2 (anti-oxidant activity) or by forming stable charge-transfer complexes with oxidized iodide species. The inhibition of LPO-catalyzed oxidation/iodination reactions by N,N-disubstituted selones can be reversed by increasing the concentration of H2O2. Interestingly, all of the N,N-disubstituted selones exhibit high anti-oxidant activities and their glutathione peroxidase (GPx)-like activity is 4-12-fold higher than that of the well-known GPx-mimic ebselen. These experimental and theoretical studies suggest that the selones exist as zwitterions, in which the imidazole ring contains a positive charge and the selenium atom carries a large negative charge. Therefore, the selenium moieties of these selones possess highly nucleophilic character. The 77Se NMR chemical shifts for the selones show large upfield shift, thus confirming the zwitterionic structure in solution. Stop, in the name of love: The inhibition of lactoperoxidase (LPO)-catalyzed reactions by a series of N,N-disubstituted thiones and selones that contain an imidazole pharmacophore is described. The inhibitory activity not only depends on the substituent that is attached to the nitrogen atom, but also on the nature of the chalcogen atom. The inhibition of LPO activity by selones is due to their ability to scavenge the substrate, hydrogen peroxide. Copyright

Dication Ethers and Related Compounds, 1. On Dication Chalkogenides and Dichalkogenides

Reaction of N,N-, N,S-, S,S-, and O,O-substituted thiones 4a-f or selones 6a-c with trifluoromethanesulfonic anhydride leads to dication disulfides 5a-f or diselenides 7a-c, resp.No dication sulfides or selenides are obtained whose formation would parallel the reactivity of the corresponding urea derivatives.This class of dications (14, 15) is, on the other hand, accessible by the reaction of dication ethers 13 with thiones 4 or selones 6. 1H and 13C NMR data of the dication dichalkogenides and chalkogenides are compared with each other.

Extremely Reactive C=C-Double Bonds, II. 1,3-Diphenyl-2-imidazolidineselenone from 1,1',3,3'-Tetraphenyl-Δ2,2'-biimidazolidine and Selenium

1,1',3,3'-Tetraphenyl-Δ2,2'-biimidazolidine (1) reacts with metallic selenium to form 1,3-diphenyl-2-imidazolidineselenone (6).The actions of powdered copper, ethyliodide, thiophenol, phenyl magnesiumbromide, phenylisocyanate, and lithium alanate on 6 are described.Some of the unusual mechanisms of these reactions are discussed.