86453-94-3

Upstream product

• 1123-49-5 3,5-dimethyl-4-nitroisoxazole 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 77533-55-2 3-Methyl-5-((E)-2-o-tolyl-vinyl)-isoxazol-4-ylamine 
• 86453-99-8 5-(1,2-Dibromo-2-o-tolyl-ethyl)-3-methyl-4-nitro-isoxazole 
• 1370018-87-3 7,7'-(2-methylphenylmethylene)bis(3-methyl-6-phenylisoxazolo[4,5-b]pyridine-N-oxide) 

Relevant academic research and scientific papers

Multi-component synthesis of methylene bis isoxazolo[4,5-b]-pyridine-N- oxides

A three component one-pot protocol was investigated for the synthesis of methylene bis isoxazolo[4,5-b]-pyridine-N-oxides from commercially available materials.

Phosphine-Catalyzed [3 + 2] Annulation of Morita-Baylis-Hillman Carbonates with Isoxazole-Based Alkenes

A phosphine-catalyzed [3 + 2] annulation of Morita-Baylis-Hillman (MBH) carbonates with 3-methyl-4-nitro-5-styrylisoxazoles has been developed to afford various multifunctional isoxazoles in moderate to good yields with moderate to excellent diastereoselectivities. With a spirocyclic chiral phosphine as the catalyst, up to 89% ee was obtained.

Multi-component synthesis and in vitro and in vivo anticancer activity of novel arylmethylene bis-isoxazolo[4,5-b]pyridine-N-oxides

A three component one-pot protocol has been investigated for the synthesis of arylmethylene bis-isoxazolo[4,5-b]pyridine-N-oxides 1 from the commercially available materials. The title compounds 1 were also synthesized by a step-wise method and found to b

A fast and highly efficient protocol for synthesis of pyrrolo[2,3-d] isoxazoles and a new series of novel benzyl bis-pyrrolo[2,3-d]isoxazoles using task-specific ionic liquids as catalyst and green solvent

We report a mild, fast, highly efficient and eco-friendly protocol for the green synthesis of pyrrolo[2,3-d]isoxazoles and a new series of novel benzyl bis-pyrrolo[2,3-d]isoxazoles from nitro styrylisoxazoles in SnCl 2-ionic liquid by reductive