86474-52-4Relevant academic research and scientific papers
IMINO SULFANONE INHIBITORS OF ENPP1
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Paragraph 0181, (2021/11/13)
The present disclosure relates generally to inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to sulfoximine- based inhibitors of ENPP1 of Formula (I) and methods of their use for treating disease mediated by ENPP1.
Synthesis of Some 3-Cyano-2-methylquinolin-4-ones
Khan, Misbahul A.,Jorge, Tereza C. M.
, p. 333 - 338 (2007/10/02)
The condensation of ethyl 2-cyano-3-ethoxycrotonate with various anilines gave the corresponding anilinocrotonates which were cyclized in refluxing Dowtherm "A" to give the title quinolones. - Keywords: Ethyl 3-anilino-2-cyanocrotonates; Ethyl 2-cyano-3-e
