864754-08-5

Usage

Molecular composition

Consists of fluorine, nitrogen, oxygen, boron, and carbon elements.

Structural complexity

Has a long and specific chemical name, indicating a complex molecular structure.

Amide functional group

Presence of the amide group suggests potential pharmaceutical or agricultural applications, as it is commonly found in drugs and herbicides.

Boron content

The presence of boron suggests potential use in materials science or organoboron chemistry.

Trifluoro group

Indicates that the compound may have unique physical and chemical properties, which can be beneficial in various applications.

Upstream product

• 407-25-0 trifluoroacetic anhydride 
• 214360-73-3 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline 

Downstream Products

• 214360-73-3 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline 
• 887757-45-1 2,2,2-trifluoro-N-methyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide 

Relevant academic research and scientific papers

Photoredox-Catalyzed Defluorinative Functionalizations of Polyfluorinated Aliphatic Amides and Esters

Selective C?F bond functionalization of perfluoalkyl units has huge potential towards accessing functionalized organofluorinated compounds, but remains challenging due to the high C?F bond strength and inherent selectivity challenges. We report a new catalytic approach to the selective functionalization of strong C?F bonds in polyfluorinated aliphatic esters and amides. This simple reaction proceeds in mild and operational fashion with divergent conversions, including hydrodefluorination, defluoroalkylation, and defluoroalkenylation, affording a diverse array of important partially fluorinated motifs. Straightforward downstream chemistry towards fluorinated alcohols, amines and drug derivatives highlights the potential of the protocol.

2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION

A 2,3,4,5-tetrahydro-1H-1,5-benzodiazepine derivative represented by the generalformula (1): [Chemical formula 1] (1) or a pharmaceutically acceptable saltthereof. They are useful as a therapeutic/preventive agent for diabetes, diabeticnephropathy, or glomerulosclerosis.