864825-79-6Relevant academic research and scientific papers
Rapid Room-Temperature, Chemoselective Csp2?Csp2Coupling of Poly(pseudo)halogenated Arenes Enabled by Palladium(I) Catalysis in Air
Kalvet, Indrek,Magnin, Guillaume,Schoenebeck, Franziska
supporting information, p. 1581 - 1585 (2017/02/05)
While chemoselectivities in Pd0-catalyzed coupling reactions are frequently non-intuitive and a result of a complex interplay of ligand/catalyst, substrate, and reaction conditions, we herein report a general method based on PdIthat allows for an a priori predictable chemoselective Csp2?C Csp2coupling at C?Br in preference to C?OTf and C?Cl bonds, regardless of the electronic or steric bias of the substrate. The C?C bond formations are extremely rapid (Idimer under open-flask conditions.
PYRAZOLOQUINOLINE DERIVATIVES
-
Paragraph 0547; 0548, (2013/06/26)
A compound and/or pharmacologically acceptable salt thereof represented by the formula (I) has PDE9 inhibitory action, so that the intracerebral cGMP concentration is anticipated to be elevated. The PDE9 inhibitory action and the increase in cGMP lead to the improvement of learning and memory behaviors, and the compound (I) has applicability as a therapeutic agent for cognitive dysfunctions in Alzheimer's disease. wherein R1 is a hydrogen atom; R2 is an aromatic ring group, etc.; R3 is a hydrogen atom, etc; R4 is a hydrogen atom; R5 is an oxepanyl group, etc.; R6 is a hydrogen atom.
Fused polycyclic compound and organic light-emitting device using the compound
-
Page/Page column 26-27, (2012/12/14)
Provided are fused polycyclic compounds suitable for use mainly as a component for a blue-light-emitting device, and an organic light-emitting device using the compound. The fused polycyclic compounds are represented by the general formulae (1), (2), (8) and (9).
PROCESS FOR THE PREPARATION OF PROTECTED L-ALANINE DERIVATIVES
-
Page/Page column 30, (2010/06/17)
The present invention is directed to a novel process for the preparation of protected L-alanine derivatives, useful as intermediates in the synthesis of compounds useful as mu/delta opioid modulators.
PROCESS FOR THE PREPARATION OF OPIOID MODULATORS
-
Page/Page column 26; 33, (2008/06/13)
The present invention is directed to novel processes for the preparation of opioid modulators (agonists and antagonists) and intermediates in their synthesis. The opioid modulators are useful for the treatment and prevention of as pain and gastrointestina
NOVEL COMPOUNDS AS OPIOID RECEPTOR MODULATORS
-
Page/Page column 45, (2010/02/13)
The present invention is directed to novel opioid receptor modulators of Formula (I). The invention further relates to methods for preparing such compounds, pharmaceutical compositions containing them, and their use in the treatment of disorders that may
