864829-89-0

Upstream product

• 821768-11-0 1,2,3,6-tetrahydro-4-(2-methylphenyl)-1-(phenylmethyl)-pyridine 
• 83674-75-3 1-benzyl-4-o-tolylpiperidin-4-ol 
• 932-31-0 ortho-tolylmagnesium bromide 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 95-46-5 2-methylphenyl bromide 

Relevant academic research and scientific papers

CYCLOALKANOPYRIDINE DERIVATIVE

Provided are cycloalkanopyridine derivatives of formula [I]: [wherein the symbols are the same as those stated in the description]. The compounds act as a nociceptin receptor antagonist, and are useful as medicines for diseases associated with a nociceptin receptor, for example, as a reliever against tolerance to a narcotic analgesic; a reliever against dependence on or addiction to a narcotic analgesic; an analgesic enhancer; an antiobesitic or appetite suppressor; a treating or prophylactic agent for cognitive impairment and dementia/amnesia; an agent for treating developmental cognitive abnormality; a remedy for schizophrenia; an agent for treating neurodegenerative diseases; an anti-depressant or treating agent for affective disorder; a treating or prophylactic agent for diabetes insipidus; a treating or prophylactic agent for polyuria; or a remedy for hypotension.