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Dopexamine hydrochloride is a synthetic dopamine analog that functions as a β2-adrenergic receptor agonist and an agonist at peripheral dopamine receptors. It is a pharmaceutical compound designed to enhance myocardial and renal performance in specific patient populations.
Used in Pharmaceutical Industry:
Dopexamine hydrochloride is used as a therapeutic agent for improving myocardial and renal performance in patients with low cardiac output states. Its dual action on β2-adrenergic and dopamine receptors helps to increase cardiac output and maintain renal blood flow, which is crucial for the management of such conditions.

86484-91-5

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86484-91-5 Usage

Clinical Use

Inotropic support in exacerbations of heart failure and heart failure associated with cardiac surgery

Drug interactions

Potentially hazardous interactions with other drugsAnaesthetics: risk of ventricular arrhythmias with isoflurane - avoid.Antidepressants: risk of hypertensive crisis with MAOIs and moclobemide.Beta-blockers: risk of severe hypertensionDopaminergics: avoid with rasagiline.Sympathomimetics: effects of adrennoradrenaline possibly enhanced.

Metabolism

Dopexamine is rapidly eliminated from blood with a halflife of approximately 6-7 minutes in healthy volunteers and around 11 minutes in patients with cardiac failure. Subsequent elimination of the metabolites is by urinary and biliary excretion.

Check Digit Verification of cas no

The CAS Registry Mumber 86484-91-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,4,8 and 4 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 86484-91:
(7*8)+(6*6)+(5*4)+(4*8)+(3*4)+(2*9)+(1*1)=175
175 % 10 = 5
So 86484-91-5 is a valid CAS Registry Number.
InChI:InChI=1/C22H32N2O2.2ClH/c25-21-11-10-20(18-22(21)26)13-17-24-15-7-2-1-6-14-23-16-12-19-8-4-3-5-9-19;;/h3-5,8-11,18,23-26H,1-2,6-7,12-17H2;2*1H

86484-91-5 Well-known Company Product Price

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  • Sigma-Aldrich

  • (Y0000612)  Dopexamine dihydrochloride  European Pharmacopoeia (EP) Reference Standard

  • 86484-91-5

  • Y0000612

  • 1,880.19CNY

  • Detail

86484-91-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Dopexamine Hydrochloride

1.2 Other means of identification

Product number -
Other names 4-[2-[6-(2-phenylethylamino)hexylamino]ethyl]benzene-1,2-diol,dihydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86484-91-5 SDS

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