864852-81-3Relevant academic research and scientific papers
Stereoselective synthesis of constrained azacyclic hydroxyethylene isosteres as aspartic protease inhibitors: Dipolar cycloaddition and related methodologies toward branched pyrrolidine and pyrrolidinone carboxylic acids
Hanessian, Stephen,Yun, Hongying,Hou, Yihua,Tintelnot-Blomley, Marina
, p. 6746 - 6756 (2005)
The synthesis of three vicinally substituted azacyclic carboxylic acids in enantiopure form was achieved from a common α-amino aldehyde originating from L-leucine. Pyrrolidines and pyrrolidinones were elaborated from α,β-unsaturated γ-hydroxy-δ-amino acid
