864909-80-8

Upstream product

• 864909-79-5 (R)-1,5-diisopropenyl-2-methyl-cyclohex-2-enol 
• 6485-40-1 (R)-Carvone 

Downstream Products

• 864909-81-9 (1S,5S)-3,5-Diisopropenyl-2-methyl-cyclohex-2-enol 
• 38655-85-5 (-)-β-elemene-6-one 
• 864909-82-0 ((1S,5R)-1,5-Diisopropenyl-2-methyl-cyclohex-2-enyl)-acetic acid ethyl ester 
• 864909-93-3 2-((1S,5R)-1,5-Diisopropenyl-2-methyl-cyclohex-2-enyl)-ethanol 
• 864909-78-4 ((1S,5R)-1,5-Diisopropenyl-2-methyl-cyclohex-2-enyl)-acetaldehyde 

Relevant academic research and scientific papers

Synthesis of beta-elemene, intermediates thereto, analogues and uses thereof

The present invention provides convergent processes for preparing beta-elemene, and analogues thereof. Also provided are analogues related to beta-elemene and intermediates useful for preparing the same. The present invention further provides novel compositions based on analogues of beta-elemene and methods for the treatment of cancer, such as brain tumor, lung cancer, colorectal cancer, gastric intestional cancer, and stomach cancer.

Competitive formation of spiro[5.5]undecane in preference to bicyclo[4.3.1]decane via type II carbonyl ene reaction

The presence of an isopropenyl group at the C-1 position of a 3-isopropenylcyclohexaneacetaldehyde failed to generate the spiro[4.5]decane and produced only bicyclo[4.3.1]decanol. However, the presence of a methallyl group at the C-1 position of 3-isoprop