864914-98-7

Upstream product

• 864914-96-5 (1S,4S)-4-hydroxymethyl-2,2-dimethylcyclobutan-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 864914-95-4 (2R)-N-[3,3-dimethyl-4,4-bis(trimethylsilyloxy)cyclobutanecarbonyl]-bornane-10,2-sultam 
• 864914-94-3 (2R)-N-[3,3-dimethyl-4,4-bis(trimethylsilyloxy)cyclobut-1-enecarbonyl]-bornane-10,2-sultam 

Downstream Products

• 864915-16-2 (1R,4S,5S)-4-[(E)-(1S,2S)-6-(tert-Butyl-diphenyl-silanyloxy)-1-hydroxy-2-methoxy-4-methyl-hex-3-enyl]-7,7-dimethyl-2-oxa-bicyclo[3.2.0]heptan-3-one 
• 864915-15-1 (1R,4S)-4-[(tert-butyldiphenylsilyloxy)methyl]-2,2-dimethylcyclobutan-1-ol 
• 864915-08-2 Toluene-4-sulfonic acid (1S,2R)-2-(2-ethoxy-ethoxy)-3,3-dimethyl-cyclobutylmethyl ester 
• 864915-07-1 (1R,4S)-2,2-dimethyl-4-[(p-toluenesulfonyloxy)methyl]lcyclobutan-1-ol 
• 864914-99-8 (4S)-4-[(tert-butyldiphenylsilyloxy)methyl]-2,2-dimethylcyclobutan-1-one 

Relevant academic research and scientific papers

Total syntheses of (+)- and (-)-pestalotiopsin A

(Chemical Equation Presented) An enantioselective total synthesis of both enantiomers of caryophyllene-type sesquiterpenoid pestalotiopsin A has been achieved, thereby establishing the absolute stereochemistry of natural (+)-pestalotiopsin A. Highlights o

Synthetic studies of pestalotiopsin A: Asymmetric synthesis of the 2-oxabicyclo[3.2.0]heptane substructure

A functionalized 2-oxabicyclo[3.2.0]heptan-3-one derivative, possessing all the skeletal carbons of pestalotiopsin A, has been synthesized. For the preparation of intermediary cyclobutane derivatives in enantioenriched form, the Lewis acid-catalyzed [2+2] cycloaddition of N-propiolated Oppolzer's camphorsultam with dimethylketene bis(trimethylsilyl) acetal followed by a stereoselective 1,4-hydride addition/protonation, has been developed.