864967-52-2

Upstream product

• 864967-32-8 (3R,8R,8aR)-8-allyl-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 79-22-1 methyl chloroformate 
• 56613-80-0 D-2-phenylglycinol 
• 65266-23-1 methyl 4-formylhept-6-enoate 

Downstream Products

• 864967-35-1 (3R,7R,8S,8aR)-7,8-diallyl-6-(methoxycarbonyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 864967-47-5 (3R,6R,6aR,10aS,10bR)-6-[3-(tert-Butyl-dimethyl-silanyloxy)-propyl]-5-oxo-3-phenyl-2,3,6,6a,7,10,10a,10b-octahydro-5H-oxazolo[2,3-a]isoquinoline-6-carboxylic acid methyl ester 
• 864967-48-6 (3R,6R,6aR,10aS,10bR)-6-(2-[1,3]Dioxolan-2-yl-ethyl)-5-oxo-3-phenyl-2,3,6,6a,7,10,10a,10b-octahydro-5H-oxazolo[2,3-a]isoquinoline-6-carboxylic acid methyl ester 
• 864967-46-4 (3R,6R,6aR,10aS,10bR)-6-Allyl-5-oxo-3-phenyl-2,3,6,6a,7,10,10a,10b-octahydro-5H-oxazolo[2,3-a]isoquinoline-6-carboxylic acid methyl ester 
• 864967-37-3 (3R,6aR,10aS,10bR)-6-(methoxycarbonyl)-5-oxo-3-phenyl-2,3,6,6a,7,10,10a,10b-octahydro-5H-oxazolo[2,3-a]isoquinoline 

Relevant academic research and scientific papers

A general synthetic route to enantiopure cis-fused perhydrocycloalka[c]pyridines from phenylglycinol-derived lactams

A synthetic route to enantiopure piperidines bearing a five-, six-, or seven-membered carbocyclic ring cis-fused on the c side of the heterocycle from a common phenylglycinol-derived δ-lactam is reported. Key steps are (i) a cyclocondensation reaction of

An enantioselective entry to cis-perhydroisoquinolines

(Chemical Equation Presented) An enantioselective route to cis-perhydroisoquinolines, involving a cyclocondensation reaction of (R)-phenylglycinol with a racemic oxoester, a stereoselective conjugate addition to an unsaturated bicyclic lactam, and the clo