86499-01-6Relevant articles and documents
An Improved Synthesis of 1,4-Benzo- and 1,4-Naphthoquinones Bearing Active Substituents
Syper, Ludwik,Kloc, Krystian,Mlochowski, Jacek
, p. 808 - 822 (2007/10/02)
The synthesis of 1,4-benzoquinones and 1,4-naphthoquinones 3a-j carrying substituents such as methoxyl, allyl or oxiranyl was substantially improved.The 1-methoxy-4-methoxymethyloxy 2a-d, g-k or 1,4-bis(methoxymethyloxy) derivatives 2e-f were used, as a substrates instead of 1,4-dimethoxy derivatives 1a-j hitherto used and they were oxidized with silver(II) dipicolinate.Among numerous examples, the synthesis of a new analog of ubiquinone 3d with the oxiranyl substituent, being a new bioactivated alkylating agent, is reported.