86504-24-7Relevant academic research and scientific papers
Ring-selective functionalization of N,N′-diarylureas by regioselective N-alkylation and directed ortho metalation
Clayden, Jonathan,Turner, Hazel,Pickworth, Mark,Adler, Thomas
, p. 3147 - 3150 (2005)
(Chemical Equation Presented) Unsymmetrical N,N′-diarylureas may be alkylated regioselectively at the more sterically congested nitrogen atom. The resulting mono-N-alkylated ureas undergo directed metalation (ortholithiation) with sec-BuLi to yield, on el
