865087-12-3 Usage
General Description
The chemical "(3aR,4R,5R,6aS)-4-[3S-(t-butyldimethylsiloxy)-5-phenyl-1E-pentenyl]-5-hydroxy-hexahydro-2H-cyclopenta[b]furan-2-ol" is a complex organic compound with a cyclopentafuran backbone. It has a hydroxyl group attached to the cyclopentafuran ring, as well as a pentenyl side chain with a siloxy group. The compound is stereochemically complex, with multiple chiral centers. It is highly functionalized and likely has a range of potential biological activities and synthetic applications due to its structural complexity.
Check Digit Verification of cas no
The CAS Registry Mumber 865087-12-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,5,0,8 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 865087-12:
(8*8)+(7*6)+(6*5)+(5*0)+(4*8)+(3*7)+(2*1)+(1*2)=193
193 % 10 = 3
So 865087-12-3 is a valid CAS Registry Number.
865087-12-3Relevant articles and documents
Synthesis of prostaglandin analogues, latanoprost and bimatoprost, using organocatalysis via a key bicyclic enal intermediate
Pr??vost, S??bastien,Thai, Karen,Sch??tzenmeister, Nina,Coulthard, Graeme,Erb, William,Aggarwal, Varinder K.
supporting information, p. 504 - 507 (2015/03/05)
Two antiglaucoma drugs, bimatoprost and latanoprost, which are analogues of the prostaglandin, PGF2?±, have been synthesized in just 7 and 8 steps, respectively. The syntheses employ an organocatalytic aldol reaction that converts succinaldehyde into a key bicyclic enal intermediate, which is primed for attachment of the required lower and upper side chains. By utilizing the crystalline lactone, the drug molecules were prepared in >99% ee.
