865156-59-8

Basic information

• Product Name: 4-broMo-6-Methylpyridin-2-ol
• Synonyms: 4-BroMo-6-Methyl-2(1H)-pyridinone
• CAS NO: 865156-59-8
• Molecular Formula: C₆H₆BrNO
• Molecular Weight: 188.02194
• Mol File: 865156-59-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 295.1±40.0 °C(Predicted)
• Appearance: /
• Density: 1.622±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 10?+-.0.10(Predicted)
• CAS DataBase Reference: 4-broMo-6-Methylpyridin-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-broMo-6-Methylpyridin-2-ol(865156-59-8)
• EPA Substance Registry System: 4-broMo-6-Methylpyridin-2-ol(865156-59-8)

Safety Data

• Hazardous Substances Data: 865156-59-8(Hazardous Substances Data)

Usage

General Description

4-bromo-6-methylpyridin-2-ol is a chemical compound with the molecular formula C6H6BrNO. It is a derivative of pyridine and contains a bromine atom, a methyl group, and a hydroxyl group attached to the pyridine ring. 4-broMo-6-Methylpyridin-2-ol is used in various chemical and pharmaceutical applications, including as an intermediate in the synthesis of organic compounds and in the production of pharmaceutical drugs. Its chemical properties make it useful in the development of new materials and products. Additionally, it has potential biological activities and may have applications in the field of medicinal chemistry. Overall, 4-bromo-6-methylpyridin-2-ol is a versatile chemical with a range of potential uses in different industries.

Upstream product

• 3749-51-7 4-hydroxy-6-methyl-2-pyridone 
• 3749-51-7 2,4-dihydroxy-6-methylpyridine 

Downstream Products

• 1083169-00-9 4-bromo-2-methoxy-6-methylpyridine 

Relevant articles and documents

Preparation method of 4-bromo-6-chloropyridine-2-carboxylic acid

The invention relates to a preparation method of 4-bromo-6-chloropyridine-2-carboxylic acid. The preparation method of the 4-bromo-6-chloropyridine-2-carboxylic acid comprises the following steps: carrying out primary substitution reaction on 2,4-dihydroxy-6-methylpyridine and one of phosphorus oxybromide, phosphorus pentabromide or tetrabutylammonium bromide to generate 2-hydroxy-4-bromo-6-methylpyridine; carrying out secondary substitution reaction on the 2-hydroxy-4-bromine-6-methyl pyridine and phosphorus oxychloride or phosphorus pentachloride to generate 4-bromine-6-methyl-2-pyridine; according to the preparation method of the 4bromo 6chloropyridine 2carboxylic acid, the raw materials are cheap and easy to obtain, column chromatography purification is not needed in the reaction process, and the operation is simple and convenient.

METHODS OF USING SUBSTITUTED PYRAZOLE AND PYRAZOLE COMPOUNDS AND FOR TREATMENT OF HYPERPROLIFERATIVE DISEASES

Disclosed are methods of treating hyperproliferative disorders such as cancer, methods of arresting the cell cycle in cancer cells, methods of inhibiting glutathione synthesis in cancer cells, and associated compounds for use and uses in medicaments. In certain embodiments, the methods, uses and compounds are provided with reference to compounds of the structural formula (I), in which X1, X2, Z1, Z2, the ring system denoted by "a", R1, L1, L2, Q, L3, R3, L4, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein are especially active against cancers having a mutant KRAS gene.

IMIDAZOLOPYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES

Novel imidazo[1,2-a]pyrazine compounds are disclosed that have a formula ( I ) represented by the following:The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, arthritis, inflammation, and others.