865236-53-9

Upstream product

• 107-30-2 chloromethyl methyl ether 
• 865235-97-8 4-{1-ethyl-1-[3-methyl-4-(4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butynyl)phenyl]propyl}-2-methylphenol 
• 865235-91-2 4-[1-ethyl-1-(4-ethynyl-3-methylphenyl)-propyl]-2-methylphenol 
• 865235-89-8 trifluoromethanesulfonic acid 4-[1-ethyl-1-(4-hydroxy-3-methylphenyl)-propyl]-2-methylphenyl ester 
• 865235-90-1 4-[1-ethyl-1-(3-methyl-4-trimethylsilanylethynylphenyl)propyl]-2-methylphenol 
• 55041-27-5 3,3-bis[4-hydroxy-3-methylphenyl]pentane 

Downstream Products

• 865238-33-1 trifluoromethanesulfonic acid 4-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-methoxymethoxy-3-trifluoromethyl-1-butenyl)phenyl]propyl}-2-methylphenyl ester 
• 1420837-34-8 (S)-5-(4-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)phenyl]propyl}-2-methylphenoxy)-4-hydroxypentanoic acid sodium salt 
• 865236-54-0 (S)-5-(4-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-methoxymethoxy-3-trifluoromethyl-1-butenyl)phenyl]propyl}-2-methylphenoxymethyl)dihydrofuran-2-one 
• 865241-63-0 trifluoromethanesulfonic acid 4-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)phenyl] propyl}-2-methylphenyl ester 
• 917022-89-0 (E)-4-(4-{1-ethyl-1-[3-methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl) phenyl] propyl}-2-methylphenyl)-1,1,1-trifluoro-2-trifluoromethyl-3-buten-2-ol 
• 917025-03-7 (4'-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)phenyl]propyl}-2'-methylbiphenyl-4-yl)acetic acid methyl ester 
• 917025-38-8 (4'-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)phenyl]propyl}-3-fluoro-2'-methylbiphenyl-4-yl)acetic acid methyl ester 
• 917023-08-6 (4'-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)-phenyl]-propyl}-2'-methyl-biphenyl-4-yl)acetic acid 
• 917023-34-8 (4'-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)-phenyl]-propyl}-3-fluoro-2'-methyl-biphenyl-4-yl)acetic acid 
• 917023-36-0 [6-(4-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)-phenyl]-propyl}-2-methyl-phenyl)-pyridin-3-yl]-acetic acid 
• 917023-38-2 [2-(4-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)-phenyl]-propyl}-2-methyl-phenyl)-thiazol-4-yl]-acetic acid 
• 917025-41-3 [5-(4-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)-phenyl]-propyl}-2-methyl-phenyl)-pyridin-3-yl]-acetic acid methyl ester 
• 917025-37-7 (4'-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)-phenyl]-propyl}-2'-methyl-biphenyl-3-yl)-acetic acid methyl ester 
• 917023-33-7 (4'-{1-ethyl-1-[3-methyl-4-((E)-4,4,4-trifluoro-3-hydroxy-3-trifluoromethyl-1-butenyl)-phenyl]-propyl}-2'-methyl-biphenyl-3-yl)acetic acid 

Relevant academic research and scientific papers

Effects of fluorines on nonsecosteroidal vitamin D receptor agonists

From our research of nonsecosteroidal vitamin D3 derivatives with gamma hydroxy carboxylic acid, we identified compound 6, with two CF 3 groups in the side chain, as a most potent vitamin D receptor (VDR) agonist that shows superagon

VITAMIN D-LIKE COMPOUND

The present invention provides a compound represented by the following general formula (I): or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing such a compound, and the like. The compound or a pharmaceutically acceptable

BISPHENYL COMPOUNDS USEFUL AS VITAMIN D3 RECEPTOR AGONISTS

The present invention discloses bisphenyl compounds of the formula (I): wherein R1, R2, R3, R4, R5, R6, X, Y, W are defined herein after. These compounds are useful as pharmaceuticals.