86524-55-2Relevant academic research and scientific papers
Recyclization of 1,4-dihydropyridine derivatives in acidic medium
Stupnikova,Petushkova,Muceniece,Lūsis
, p. 41 - 49 (2007)
The recyclization of 1,4-dihydropyridines in aqueous-alcoholic hydrochloric acid medium proceeds with cleavage of a C-N bond and pyridine ring opening. Cyclohexenone derivatives are formed as a result of the subsequent intramolecular crotonic condensation of the acyclic intermediate. The leaving carbonyl substituents depart simultaneously with recyclization, depending on the acidity of the reaction medium.
