86525-75-9 Usage
Appearance
White, crystalline solid
Molecular weight
239.36 g/mol
Functionality
Beta-blocking agent
Specificity
Non-selective beta-adrenergic antagonist
Mechanism of action
Blocks the effects of adrenaline on the heart, blood vessels, and lungs
Purpose
Lowers blood pressure and reduces workload on the heart
Treatment of conditions
Hypertension, angina, and arrhythmias
Potential uses
Treatment of anxiety, migraines, and glaucoma
Check Digit Verification of cas no
The CAS Registry Mumber 86525-75-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,5,2 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 86525-75:
(7*8)+(6*6)+(5*5)+(4*2)+(3*5)+(2*7)+(1*5)=159
159 % 10 = 9
So 86525-75-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H21NO2S/c1-9-5-11(8-16-9)15-7-10(14)6-13-12(2,3)4/h5,8,10,13-14H,6-7H2,1-4H3
86525-75-9Relevant academic research and scientific papers
Synthesis and β-adrenoceptor blocking activity of thiophenic analogues of toliprolol and bevantolol and closely related compounds
Conde,Corral,Lissavetzky,et al.
, p. 151 - 154 (2007/10/02)
The synthesis of a series of 3-alkylamino-1-thienyloxy-2-propanols starting from isopropylideneglycerol and the corresponding bromothiophene is described. In a preliminary pharmacological study compound 14 is very similar to Propranolol, while compound 13, a thiophenic isoster of Toliprolol seems to be less active. On the other hand compound 15, and isoster of cardioselective Bevantolol appears to be also a cardioselective β-blocking agent.
