86541-41-5

Upstream product

• 1190-73-4 2-(acetylamino)ethanethiol 
• 86541-40-4 4-nitrobenzyl (2R,5R,6R)-3,7-dioxo-6-[1-methyl-1-(4-nitrobenzyloxycarbonyloxy)ethyl]-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 86541-72-2 (6R,7R)-7-amino-2,2-dimethyl-3-oxa-1-azabicyclo<4.2.0>octan-8-one 
• 86489-27-2 (6R,7R)-2,2-dimethyl-7-isocyano-1-aza-3-oxabicyclo[4.2.0]octan-8-one 
• 86489-24-9 (3R,4R)-3-benzyloxycarbonylamino-4-(2-hydroxyethyl)azetidin-2-one 
• 86489-22-7 (3R,4R)-3-benzyloxycarbonylamino-4-(2,2-dimethoxyethyl)azetidin-2-one 
• 86489-25-0 (6R,7R)-7-benzyloxycarbonylamino-2,2-dimethyl-1-aza-3-oxabicyclo-[4.2.0]octan-8-one 
• 86489-13-6 methyl 2-[(3R,4R)-3-(1-hydroxy-1-methylethyl)-3-isocyano-2-oxo-4-allylazetidin-1-yl]-3-methylbut-2-enoate 
• 86489-36-3 (3R,4R)-4-(2-hydroxyethyl)-3-[1-methyl-1-(4-nitrobenzyloxycarbonyloxy)ethyl]azetidin-2-one 
• 86489-35-2 (6R,7R)-2,2-dimethyl-7-[1-methyl-1-(4-nitrobenzyloxycarbonyloxy)ethyl]-1-aza-3-oxabicyclo-[4.2.0]octan-8-one 
• 86489-42-1 (3R,4R)-4-(2,2-dimethoxyethyl)-3-[1-methyl-1-(4-nitrobenzyloxycarbonyloxy)ethyl]-azetidin-2-one 
• 96701-35-8 [(3R,4R)-3-[1-Methyl-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-2-oxo-4-(2-oxo-ethyl)-azetidin-1-yl]-oxo-acetic acid methyl ester 
• 86541-39-1 4-nitrobenzyl 2-diazo-4-[(2R,3R)-3-{1-methyl-1-(4-nitrobenzyloxycarbonyloxy)-ethyl}-4-oxoazetidin-2-yl]-3-oxobutanoate 
• 86541-25-5 (6R,7R)-2,2-dimethyl-7-(1-hydroxy-1-methylethyl)-1-aza-3-oxabicyclo<4.2.0.>octan-8-one 

Relevant academic research and scientific papers

4-Substituted-2-oxoazetidine compounds

The present invention relates to novel 4-substituted-2-oxoazetidine compounds and to processes for preparing the same. These compounds are useful intermediates for preparing antibiotics having the basic skeleton of Thienamycin.

SYNTHETIC STUDIES ON CARBAPENEM ANTIBIOTICS FROM PENICILLINS. III. STEREOSELECTIVE RADICAL REDUCTION OF A CHIRAL 3-ISOCYANOAZETIDINONE: A TOTAL SYNTHESIS OF OPTICALLY ACTIVE CARPETIMYCINS

A new, efficient synthesis of the optically active carpetimycins 1 from penicillins has been achieved via, as key steps, aldol reaction of isonitrile 19, followed by n-Bu3SnH reduction.