86542-87-2

Upstream product

• 498-95-3 nipecotic acid 
• 71381-75-4 N-(tert-butyloxycarbonyl)nipecotic acid 
• 937724-78-2 C₁₅H₂₆N₂O₃ 

Downstream Products

• 1185503-08-5 C₂₈H₃₆F₃N₅O₂ 
• 86543-08-0 3-(Pyrrolidine-1-carbonyl)-piperidine-1-carbothioic acid (2-cyano-4,5-dimethoxy-phenyl)-amide 
• 80030-61-1 N-(2-Cyano-4,5-dimethoxy-phenyl)-3-(pyrrolidine-1-carbonyl)-piperidine-1-carboximidothioic acid methyl ester 

Relevant academic research and scientific papers

Quinoxalinylurea derivatives as a novel class of JSP-1 inhibitors

A series of quinoxalinylurea-based inhibitors are synthesized and shown to be the novel and potent inhibitors against Jnk Stimulatory Phosphatase-1 (JSP-1), which is a special member of dual-specificity protein phosphatase (DSP) family. Biological assay a

INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA

The present invention relates to the use of compounds as broad spectrum inhibitors of bacterial biofilm formation. In particular the invention refers to a family of compounds that block the quorum sensing system of Gram-negative and Gram-positive bacteria, a process for their manufacture, pharmaceutical compositions containing them and to their use for the treatment and prevention of bacterial damages and diseases, in particular for diseases where there is an advantage in inhibiting quorum sensing regulated phenotypes of pathogens.