865464-26-2Relevant academic research and scientific papers
Towards the second generation of Boceprevir: Dithianes as an alternative P2 substituent for 2,2-dimethyl cycloproyl proline in HCV NS3 protease inhibitors
Nair, Latha G.,Bogen, Stephane,Ruan, Sumei,Pan, Weidong,Pike, Russel,Tong, Xiao,Cheng, Kuo-Chi,Guo, Zhuyan,Doll, Ronald J.,Njoroge, F. George
, p. 1689 - 1692 (2010)
Hepatitis C (HCV) infection is a global health crisis leading to chronic liver disease. In our efforts towards a second generation HCV NS3 serine protease inhibitor with improved profile, we have undertaken SAR studies in various regions of Boceprevir inc
